For mild cases of Osteoarthritis, Hyaluronic acid injections may help to decrease pain, reduce inflammation, and improve lubrication. Osteoarthritis is the most common type of arthritis and is characterized by the degeneration of cartilage and dysfunction of joint fluid, leading to joint pain, stiffness, tenderness and a loss of flexibility. Hyaluronic acid has been used most commonly for knee osteoarthritis, but may be beneficial in other joints as well, and are considered safer than cortisone injections.